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Table 1 Proposed split genes for solving increasingly larger Hamiltonian Path Problems

From: Solving a Hamiltonian Path Problem with a bacterial computer

Directed Graph

Split Genes

3 nodes

GFP, RFP

4 nodes

GFP, RFP, β-Gal

5 nodes

GFP, RFP, β-Gal, Chl

6 nodes

GFP, RFP, β-Gal, Chl, Kan

7 nodes

GFP, RFP, β-Gal, Chl, Kan, Eryth

N nodes

N-1 Split Genes

  1. Split genes that would be needed to program a bacterial computer to find the Hamiltonian path in a directed graph with the number of nodes indicated are listed. The 3 node proposed was successfully implemented in the current study. GFP = green fluorescent protein gene, RFP = red fluorescent protein gene, β-Gal = β-galactosidase gene, Chl = chloramphenicol resistance gene, Kan = kanamycin resistance gene, Eryth = erythromycin resistance gene.