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Table 3 Basic and derived lipophilicity parameters for model compounds on 3 layer types.

From: Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics

Layer type S Rm w φ o φ n R 2 S y,x
ADBA
LO -8.84 -0.646 -0.073 0.003125-0.025 4 0.974 0.0141
LP -5.99 -4.85 -0.081 0.0025-0.0254 4 0.806 0.0495
ODS -1.41 -0.102 -0.073 0.025-0.40 5 0.915 0.0620
Naproxen
LO -6.32 -0.459 -0.073 0.003125-0.025 4 0.753 0.0350
LP -5.42 0.610 0.11 0.0025-0.10 6 0.819 0.0959
ODS -2.18 1.30 0.60 0.20-0.80 6 0.961 0.0944
Nabumetone
LO -3.95 2.58 0.66 0.55-0.70 5 0.895 0.0815
LP -3.48 2.43 0.70 0.35-0.70 5 0.986 0.0556
ODS -3.13 2.77 0.89 0.70-0.95 6 0.978 0.0438
Halofantrine
LO -8.13 8.40 1.03 0.925-0.99 5 0.738 0.120
LP -6.54 6.76 1.03 0.90-1.0 5 0.864 0.102
ODS -4.55 4.94 1.09 0.90-0.975 6 0.665 0.107