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Figure 4 | Journal of Biological Engineering

Figure 4

From: Engineering fusogenic molecules to achieve targeted transduction of enveloped lentiviral vectors

Figure 4

Transduction of engineered lentiviral vectors bearing both an antibody and FM to cell lines. 293T and 293T/CD20 cells (2 × 105) were transduced with 2 ml of fresh viral vectors (FUGW/αCD20+FM, or FUGW/Ab+FM). Transduction of 293T cells was included as control. (a) iMFI on 293T and 293T/CD20 cells transduced by the fresh viral vectors (FUGW/αCD20+FM, or FUGW/Ab+FM). (b) Titers of fresh viral vectors (FUGW/αCD20+FM) on 293T and 293T/CD20 cells. (c) p24 amount of fresh viral vectors (FUGW/αCD20+FM, FUGW/Ab+FM, and FUGW/VSVG)

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