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Figure 7 | Journal of Biological Engineering

Figure 7

From: Designing and engineering evolutionary robust genetic circuits

Figure 7

Evolutionary half-life vs. initial expression level in T9002, T9002-E, R0011 + E0240, and R0010 + E0240 circuits evolved with different inducer concentrations. (A) Evolutionary half-life vs. initial expression level is plotted in T9002 (solid black circles) and T9002-E (solid dark red diamonds) circuits evolved with different AHL concentrations. An exponential fit for the mean of each evolutionary half-life vs. initial expression data point is shown by the black line. Error bars for both the x and y-axis represent one standard deviation from the mean of eight independently evolved populations. (B) Evolutionary half-life vs. initial expression level is plotted in R0011 + E0240 (solid black circles) and R0010 + E0240 (solid red circles) circuits evolved with different IPTG concentrations. An exponential fit for the mean of each evolutionary half-life vs. initial expression data point is shown by the black line. Error bars for both the x and y-axis represent one standard deviation from the mean of eight independently evolved populations.

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