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Figure 3 | Journal of Biological Engineering

Figure 3

From: Rational design of modular circuits for gene transcription: A test of the bottom-up approach

Figure 3

Percentage fluorescence in absence of IPTG (A), and dose-response curves for the gene-circuits O 2 O 2 (B), O 1 O 1 (C), and O s O s (D). In panel (A) grey bars with standard deviations are used for the experimental data while black squares are used for the simulated responses. In panels (C) and (D), a continuous line is used for the simulated dose-response curves in presence of a residual affinity for the operator sites by induced LacI molecules, while a dotted line is used for the simulated dose-response curves when this residual affinity is turned off. The y-axis is in logarithmic scale in panel (A). The x-axis is in logarithmic scale in panels (B) to (D). All the measurements were repeated at least five times.

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