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Figure 3 | Journal of Biological Engineering

Figure 3

From: Fan-out in gene regulatory networks

Figure 3

Module interface process. The output X of an upstream module regulates the downstream-module X-specific promoter (A). The translation-degradation processes for X and its promoter regulation can be modeled as the reaction process shown in B, where P f , P b , and P T denote the numbers of free, bound, and total promoters, respectively. The reaction process is mapped to an RC-circuit with an increased capacitance by C', which is shown to be proportional to P T : C' = P T C1 with C1 a proportionality constant. This means that each promoter acts as a capacitor with a unit load of capacitance, C1. The total capacitance C T becomes the sum of the capacitance C in the isolated case and the extra capacitance C'.

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