Figure 8

ROS and LPO upon the exposure to acrolein, and inhibition by various types of chitosan nanoparticles. (A) Quantification of oxidized HE fluorescence intensity of control, acrolein-induced injury, and acrolein followed by chitosan nanoparticle treatment of PC 12 cell groups (n = 5, **P < 0.01). (B) Measurements in control, acrolein-induced injured, and acrolein followed by chitosan nanoparticles treated PC 12 cell groups (n = 5, * P < 0.05, **P < 0.01, ***P < 0.001). The addition of chitosan nanoparticles following the exposure of acrolein showed markedly decreased rate of oxidation of membrane lipids as well as lipid peroxidation.