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Table 1 Material properties used in numerical simulations, as taken from [[12]]

From: Effect of tumor shape and size on drug delivery to solid tumors

Parameter

Tissue

Baseline value

Reference

L p cm / mmHgs

Normal

0.36×10−7

Rippe et al. (1978)

 

Tumor

2.80×10−7

Jain (1987a)

k c m 2 / mmHgs

Normal

8.53×10−9

Swabb et al. (1974)

 

Tumor

4.13×10−8

Jain (1987a)

S / V c m − 1

Normal

70

Pappenheimer et al. (1951)

 

Tumor

200

Hilmas and Gilette (1974)

P B mmHg

Both

15.6

Brace and Guyton (1977)

Π B mmHg

Both

20

Brace and Guyton (1977)

Π i mmHg

Normal

10

Wiederhielm (1979)

 

Tumor

15

Jain (1987a)

σ s

Normal

0.91

Ballard and perl (1978)

 

Tumor

0.82

Curry (1984)