Table 2 The identified reactions that contribute significantly to the predicted maximum NADH production rate
Reaction ID | NADH flux (mmol/gDW/h) | Enzyme | EC. No. | Reaction | Subsystems | |
|---|---|---|---|---|---|---|
Min | Max | |||||
AKGD | 0 | 17.73 | 2-oxoglutarate dehydrogenase | 2.3.1.61 | [c] : akg + coa + nad --> co2 + nadh + succoa | Central Metabolism |
ALAD_L | 0 | 52.77 | L-alanine dehydrogenase | 1.4.1.1 | [c] : ala-L + h2o + nad --> h + nadh + nh4 + pyr | Amino Acid Metabolism |
GLUDx | 0 | 52.72 | glutamate dehydrogenase (NAD) | 1.4.1.3 | [c] : glu-L + h2o + nad <==> akg + h + nadh + nh4 | Amino Acid Metabolism |
GSADH | 0 | 52.77 | L-glutamate 5-semialdehyde dehydrogenase | 1.2.1.38 | [c] : glu5sa + h2o + nad --> glu-L + (2) h + nadh | Amino Acid Metabolism |
HDMAT7 | -0.00007 | 52.77 | Hexadecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase | 1.3.1.9 | [c] : nad + palmACP <==> h + hdeACP + nadh | Fatty Acid Synthesis |
ME1x | 0 | 52.77 | malic enzyme (NAD) | 1.1.1.37 | [c] : mal-L + nad --> co2 + nadh + pyr | Central Metabolism |
P5CD | 0 | 52.77 | 1-pyrroline-5-carboxylate dehydrogenase | 1.5.1.12 | [c] : 1pyr5c + (2) h2o + nad --> glu-L + h + nadh | Amino Acid Metabolism |
PDH | 0 | 52.77 | pyruvate dehydrogenase | 1.2.4.1 | [c] : coa + nad + pyr --> accoa + co2 + nadh | Central Metabolism |
PGCD | 0.0196 | 52.79 | phosphoglycerate dehydrogenase | 1.1.1.95 | [c] : 3pg + nad --> 3php + h + nadh | Amino Acid Metabolism |
TDMAT6 | -0.00404 | 52.77 | Tetradecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase | 1.3.1.9 | [c] : myrsACP + nad <==> h + nadh + tdeACP | Fatty Acid Synthesis |