Figure 8
From: Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition
Fluorescent photographs of Col-I stain at day 6 in the experimental groups. The flat control (A) does not show any type of organization. The 500mc group (B) shows very early signs of organization even though the individual cells have not completely chosen direction. The 250mc group (C) shows cellular distribution which is allot more organized than the previous groups. Last, the 100mc group (D) shows early signs of differentiation already at day 6. Scale bar corresponds to 100 μm. In each figure, the red lines indicate the direction of the microchannels as compared to the cell animation.