Figure 2
From: Engineering biodegradable and multifunctional peptide-based polymers for gene delivery
Synthesis of statistical HPMA-oligolysine copolymers by RAFT polymerization. HPMA and methacrylamido-functionalized oligolysine peptides are copolymerized under aqueous RAFT conditions using ethyl cyanovaleric trithiocarbonate (ECT) as the chain transfer agent (CTA) [71] and VA-044 as the initiator. The 6-carbon aminohexanoic acid (Ahx) is used as a linker between the pendant oligolysine peptide and the hydrophilic backbone.