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Figure 4 | Journal of Biological Engineering

Figure 4

From: Design and analysis of a tunable synchronized oscillator

Figure 4

Correlation between the cell density and the onset of synchronized oscillatory behavior across a population of cells. As LuxI (cyan) is produced more rapidly than AiiA (dark blue), AHL (red) will initially peak to a high level before being degraded and reaching a low basal level. At low cell densities, the AHL level is not enough to induce synchronized oscillatory behavior across a population of cells. At higher cell densities however there will be enough AHL in the system to coordinate the dynamic expression of the oscillatory construct within the cells, thus sustained oscillations in GFP levels will be observed.

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