Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale

Table 2 Properties of the utilized disposable reactor systems

Product name	Nominal volume	Reactor diameter (d)	Material	Shaking platform	N_cfor V_L = 20% (Eq.2)
Corning roller bottle, 850 cm², easy grip vent cap	2 L	116.3 mm	PS^b	Kühner ISF1-X	147 rpm
Nalgene 10 L Clearboy	10 L	240 mm	PC^c	Kühner SR 200-X Pilot-Shaker	77 rpm
Nalgene 20 L Carboy	20 L	286 mm	PP^a	Kühner SR 200-X Pilot-Shaker	76 rpm
Nalgene 50 L Carboy	50 L	379 mm	PP^a	Kühner SR 200-X Pilot-Shaker	69 rpm
Sartorius 200 L CultiBag ORB	200 L	750 mm	LDPE^d/EVOH^e/EVA^f	Kühner SB 200-X OrbShake	35 rpm

^a PP: Polypropylene, ^b PS: Polystyrene, ^c PC: Polycarbonate, ^d LDPE: Low density polyethylene, ^e EVOH: Ethyl vinyl alcohol, ^f EVA: Ethylene-vinyl acetate.