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Table 2 Parameters of solute transport model used in numerical simulations

From: Effect of tumor shape, size, and tissue transport properties on drug delivery to solid tumors

Parameter

Baseline value

Reference

σf

  Normal

0.9

[8]

  Tumor

0.9

D eff [m2/s]

  Normal

0.16× 10−12

[8]

  Tumor

2.0× 10−12

P[m/s]

  Normal

2.2× 10-10*

[8]

  Tumor

17.3× 10-10*

Ï„ [hr]**

  Plasma

6.1

[8]

  1. *- the microvessel permeability coefficient is 10% of effective permeability introduced in [8].
  2. **- the drug half-life in plasma introduced in results section.
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Journal of Biological Engineering

ISSN: 1754-1611