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Table 1 Growth ability of epithelial cells cultured for 48 h on micropatterned substrates with pillar and pit

From: Influence of surface topography on the human epithelial cell response to micropatterned substrates with convex and concave architectures

Locational classification of convex or concave in vertical direction

Pillar substrate

Pit substrate

 

Ratio of increased cell number,X48/X24(-)

Ratio of dividing cells,Rd(10-2)

Ratio of increased cell number,X48/X24(-)

Ratio of dividing cells,Rd(10-2)

RTA region

1.8 ± 0.8

91.3 ± 7.3

1.8 ± 0.5

94.0 ± 3.9

  R1 region

3.9 ± 1.8

90.9 ± 8.4

2.7 ± 1.4

89.2 ± 8.0

  R2 region

1.4 ± 1.0

91.4 ± 7.1

1.5 ± 0.4

94.3 ± 5.6

Flat Region

2.1 ± 0.7

84.0 ± 8.4

2.6 ± 0.6

96.1 ± 2.1

  1. Measurements were made in an individual 9 pillars and pits. Data are expressed as means ± standard deviation from triplicate measurements and analyzed using Student’s t-test. There were no statistically significant differences among the data sets.
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Journal of Biological Engineering

ISSN: 1754-1611