Figure 1

Designs of MTP well geometries (48-well plate format). (A) 3 different sets of well geometries represent the gradual transition from the most pronounced baffling (square and pentagon geometry, respectively) to the least pronounced geometry (round geometry); (B) 3 groups of well designs attained by introducing different types of baffles in round (baffled cylinders) or edged (star and flower shapes) well geometries. All geometries have an equivalent cross-section area of 112 mm². The diameters of the edge roundings or the introduced half-circular baffles are given in parentheses. Further design details can be found in Funke et al. (2009) [12]; (C) Geometries described in (A) and (B) sorted according to their perimeter relative to the round well geometry.