In silico design and in vivoimplementation of yeast gene Boolean gates

Table 1 Basic Boolean gates’ performance

Gate	Input	1	max(0)	σ	ρ	φ	0/1 th.
YES tetOp	tet	6500	1899	4601	3.42	0.96	4000
YES tetOp2	tet	4305	655	3640	6.57	1.10	2500
YES lacOp	IPTG	6190	1260	4930	4.91	1.22	3500
YES lacOp2-DI	IPTG	916	34	882	26.94	0.19	500
NOT lexOp	estr	6158	995	5163	6.19	0.93	3000
NOT lexOp2	estr	2801	164	2637	17.04	0.95	1500
AND lexOp-tetOp	tet, estr	6052.5	1641.5	4411	3.96	1.16	3000
AND tetOp-lexOp	tet, estr	4968	1245	3723	3.99	0.84	3000
AND tetOp-lacOp	tet, IPTG	2968	952	2016	3.12	0.73	2000
AND lacOp-tetOp-TI	tet, IPTG	3441.5	1424	2017.5	2.42	0.27	2250
AND lexOp-lacOp	IPTG, estr	1308	285	1023	4.90	0.46	750
AND lacOp-lexOp	IPTG, estr	1489	223	1266	6.68	0.31	900

All the fluorescence levels are expressed in arbitrary units. The last column reports the values chosen for the 0/1 threshold.

ISSN: 1754-1611