Table 4 Effects of Se-CEPS on the body weight, tumor growth in CT26-bearing mice (n = 8, *p < 0.05 vs model group)
Group | Dosage(mg/kg) | Body weight(g) | Tumor weight(g) | Inhibitory rate(%) |
|---|---|---|---|---|
Model control | — | 20.34 ± 2.13 | 1.34 ± 0.31 | — |
5-FU group | 20 | 16.21 ± 1.86* | 0.47 ± 0.16* | 64.93 |
CEPS group | 50 | 20.27 ± 0.98 | 1.27 ± 0.28 | 5.22 |
100 | 20.04 ± 2.01 | 1.03 ± 0.19 | 23.13 | |
200 | 20.13 ± 1.46 | 0.91 ± 0.33 | 32.09 | |
Se-CEPS group | 50 | 20.72 ± 2.14 | 1.06 ± 0.25 | 20.90 |
100 | 20.41 ± 0.79 | 0.82 ± 0.14 | 38.81 | |
200 | 20.42 ± 1.68 | 0.64 ± 0.09* | 52.24 | |
Se-CEPS + 5-FU group | 200(Se-CEPS) + 20(5-FU) | 18.15 ± 2.17* | 0.36 ± 0.17* | 73.13 |