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Fig. 4 | Journal of Biological Engineering

Fig. 4

From: Directing three-dimensional multicellular morphogenesis by self-organization of vascular mesenchymal cells in hyaluronic acid hydrogels

Fig. 4

a The mechanical property of the HA hydrogel used in this experiment. b The volume ratio of the multicellular structure to the 3D matrix for the three types of multicellular structures. The cell occupied volume fractions (COVF, mean ± SD) for the three types of multicellular structures had statistically significant difference between each other. * P < 0.03 versus the control 3D networks, n = 4; # P < 0.001 versus the control 3D networks, n = 4. c Geometric parameter values including the characteristic length of network and the diameter of multicellular spheroid for three experimental groups. The characteristic lengths (mean ± SD) between adjacent network nodes had statistically significant difference in control and 3D thicker network samples. ** P < 0.05; n =20

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