Modeling the architecture of the regulatory system controlling methylenomycin production in Streptomyces coelicolor

Table 1 The effects of knocking out certain genes and combinations of genes observed experimentally, adapted from [9]

The wildtype strain is allocated a single ‘+’ to denote typical methylenomycin expression. Over-expression and the cessation of expression are denoted by ‘+++’ and ‘-’ respectively

ISSN: 1754-1611