Skip to main content

Table 1 The effects of knocking out certain genes and combinations of genes observed experimentally, adapted from [9]

From: Modeling the architecture of the regulatory system controlling methylenomycin production in Streptomyces coelicolor

S. coelicolor strain Methylenomycin production
Wildtype +
Δ mmyR +++
Δ mmfLHP -
Δ mmfLHP+ Δ mmyR+ Δ mmfR +++
Δ mmfLHP+exogenous MMF +
  1. The wildtype strain is allocated a single ‘+’ to denote typical methylenomycin expression. Over-expression and the cessation of expression are denoted by ‘+++’ and ‘-’ respectively