Fig. 1
From: Climbing the mountain: experimental design for the efficient optimization of stem cell bioprocessing
Yield and Sensitivity in Bioprocesses. Despite a high purity (top), it is important that the absolute yield (output cell per input cell; bottom) is also taken into account for a bioprocess to be commericially viable (a). Depending on the sensitivity of the system, the same change in one variable (here indicated by a shift along the x-axis) can result in very different responses (z-axis), a parameter that is important for reproducibility of a given process (b)