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Fig. 8 | Journal of Biological Engineering

Fig. 8

From: Modeling the behavior of human induced pluripotent stem cells seeded on melt electrospun scaffolds

Fig. 8

Numerical simulations of population dynamics. Top: Population dynamics with initial population of 5000 progenitor cells for C=7.7 (solid) and C=6 (dash) with O=21 and W=5. Experimental parameters (×10−5): \(\bar {\alpha }=0.01,\bar {\beta }=0.16, \bar {\gamma }=0.16,\bar {p_{1}}=119, \bar {p_{2}}=160, \bar {d_{1}}=13.5, \bar {d_{2}}=7.745, \bar {r}=0.1\). Middle: Population dynamics with initial population of 5000 stem cells and C=10 for O=21 (solid) and O=5 (dash). Same experimental parameters used as for top simulation. Bottom: Population dynamics after switching to parameters for maximizing D from the initial point of S , with independent d 1, d 2, and r. See Fig. 7 for parameters used in maximizing S , and simulation at top for D maximizing parameters

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