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Fig. 1 | Journal of Biological Engineering

Fig. 1

From: Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure

Fig. 1

Synthesis, metabolism and function of natriuretic peptides. Abbreviations: ANP: atrial natriuretic peptide; BNP: B-type natriuretic peptide; cGMP: cyclic guanosine monophosphate; CNP: C-type natriuretic peptide; DPP-4: dipeptidyl peptidase-4; GC: guanylate cyclase; GTP: guanosine triphosphate; IDE: insulin degrading enzyme; NEP: neutral endopeptidase; NPR: natriuretic peptide receptor; NT-proANP: N-terminal proANP; NT-proBNP: N-terminal proBNP; NT-proCNP: N-terminal proCNP; PDE: phosphodiesterase; PKG: protein kinase; RAAS: renin-angiotensin-aldosterone system; SNS: sympathetic nervous system

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