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Fig. 1 | Journal of Biological Engineering

Fig. 1

From: Optimization of fermentation conditions for an Escherichia coli strain engineered using the response surface method to produce a novel therapeutic DNA vaccine for rheumatoid arthritis

Fig. 1

a, b Single-factor analysis of basal culture medium revealed optimal carbon and nitrogen sources for producing therapeutic DNA vaccine pcDNA-CCOL2A1. a Evaluation of the optimal basal culture medium among LB, 2 × YT, TB, M9 (Glycerol) and M9 (Glucose) in shaking flask culture through One-Way ANOVA. b Screen the optimal carbon and nitrogen sources in shaking flask culture using One-Way ANOVA. *p < 0.05, * * p < 0.001. Data are expressed as the mean ± standard deviation (SD) of 3 independent experiments

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