Fig. 7From: CD24 identifies nucleus pulposus progenitors/notochordal cells for disc regenerationHIF-1α-NOTCH1 pathway activation is essential for CD24+ NP cells maintenance. a-b Western blot analysis of JAGGED-1, NOTCH1 and HES-1 expression in CD24+, CD24− and unsorted NP cells. (c) Quantification analysis of JAGGED-1, NOTCH1 and HES-1 mRNA expression in CD24+, CD24− and unsorted NP cells. d-e Fluorescence activated cell sorting analysis of the percentage of CD24+ NP cells after Hif-1α or Vhl knock down with or without DAPT and JAGGED-1 stimulation. *P < 0.05, **P < 0.01, ***P < 0.001. P-values were analyzed by one-way ANOVABack to article page