Fig. 4From: Inhibition of bacterial toxin recognition of membrane components as an anti-virulence strategyInhibition of pore formation and requisite conformational changes. a Blocking the pore formed from the anthrax PA toxin inhibits translocation of the enzymatic subunits (EF and LF) into the host cell. b A peptide inhibitor binds to the CROP domain of the TcdB toxin, destabilizing the protein by preventing the conformational changes required for cytotoxic activityBack to article page