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Fig. 4 | Journal of Biological Engineering

Fig. 4

From: Transplantation of CRISPRa system engineered IL10-overexpressing bone marrow-derived mesenchymal stem cells for the treatment of myocardial infarction in diabetic mice

Fig. 4

Transplantation of BM-MSCs pCas9/gIL10 improves cardiac functional recovery in mice model of diabetic MI. a Representative echocardiographic images 4 weeks after MI and treated with BM-MSCs-pCas9/gCtrl, pCas9/gIL10 or BM-MSCs-pCas9/gIL10. b Left ventricular ejection fraction (LVEF). Data represent means ± SD. *p < 0.05, **p < 0.005, n = 8. c-e Hemodynamic analyses including +dp/dtmax, −dp/dtmax, and LV end diastolic pressure (LVEDP). Data represent means ± SD. *p < 0.05, **p < 0.005, n = 8

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Journal of Biological Engineering

ISSN: 1754-1611