Fig. 1
From: Novel biomanufacturing platform for large-scale and high-quality human T cells production
Diagram of scalable human T cell biomanufacturing in stirred-tank bioreactor. Seed culture was carried out in shaker flask for 1st stimulation and cell expansion until enough cells were generated to inoculate bioreactor. Each bioreactor culture was initiated on Day 0 and allowed cell expansion for 4 days. The 2nd stimulation (optional) was performed in bioreactor or shaker flask