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Fig. 1 | Journal of Biological Engineering

Fig. 1

From: Genetic circuits to engineer tissues with alternative functions

Fig. 1

Tools in synthetic biology to drive stem cell differentiation. Genetic tools built by synthetic biologists enable tight control of gene expression that allow the dynamic control of transcription factor expression in stem cells. This includes various levels of expression (e.g. low, medium, and high), in addition to controlling levels of expression in dynamic patterns including tuning, pulsing, oscillations, etc. Controlling the levels, timing, and patterns of gene expression at various checkpoints of stem cell fate improves differentiation outcomes

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