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Table 4 Test matrix developed for conducting the study

From: Mixture theory modeling for characterizing solute transport in breast tumor tissues

Configuration

Flow Direction Type

Intercapillary separation (μm)

Solute Molecular weight (kDa)

Test 1: Effect of solute size

 SBC

N/A

N/A

0.1, 3.0, 10.0, 40.0, 70.0

 2 BC

CO

100

0.1, 3.0, 10.0, 40.0, 70.0

 BC_LC

CO

100

0.1, 3.0, 10.0, 40.0, 70.0

Test 2: Effect of flow direction in microvessels

 2 BC

CO

100

0.1, 3.0, 10.0, 40.0, 70.0

 2 BC

CN

100

0.1, 3.0, 10.0, 40.0, 70.0

 BC_LC

CO

100

0.1, 3.0, 10.0, 40.0, 70.0

 BC_LC

CN

100

0.1, 3.0, 10.0, 40.0, 70.0

Test 3: Effect of intercapillary separation

 SBC

N/A

N/A

3.0, 10.0

 2 BC

CO

10,50,100,250,1250

3.0, 10.0

 BC_LC

CO

10,50,100,250,1250

3.0, 10.0