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Fig. 7 | Journal of Biological Engineering

Fig. 7

From: Construction of an immunotoxin via site-specific conjugation of anti-Her2 IgG and engineered Pseudomonas exotoxin A

Fig. 7

Binding of the trastuzumab-PE24 conjugate to Fc-receptors measured by ELISA: (a) hC1q, (b) FcRn at pH 6.0, (c) FcRn at pH 7.4, (d) FcrRI, (e) FcrRIIa(H), (f) FcrRIIa(R), (g) FcrRIIb, (h) FcrRIIIa(F), (i) FcrRIIIa(V). hC1q: complement component 1q; FcRn: neonatal Fc receptor; FcrRI: Fc gamma receptor I; FcrRIIa(H): Fc gamma receptor IIa (H134); FcrRIIa(R): Fc gamma receptor IIa (R134); FcrRIIb: Fc gamma receptor IIb; FcrRIIIa(F): Fc gamma receptor IIIa (F158); FcrRIIIa(V): Fc gamma receptor IIIa (V158). The analyses were done three times, and the error bars represent one standard deviation

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