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Fig. 5 | Journal of Biological Engineering

Fig. 5

From: Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy

Fig. 5

Targeting of EcN to tumor tissues after systemic administration. a Fluorescent luminescence detection of EcN (Lux) at different concentrations. b EcN (Lux) was systematically injected to BALB/c nude mice bearing SMMC-7721 tumor cells. For control, EcN (Lux) was injected to healthy BALB/c nude mice with no tumor. Whole body distributions of the injected EcN (Lux) were observed using in vivo imaging system spectrum 72 h after the injection. c Spleen, liver, kidney, lung, heart, intestine, and tumor tissues were isolated to investigate the bioluminescence signals in different organs

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Journal of Biological Engineering

ISSN: 1754-1611