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Fig. 7 | Journal of Biological Engineering

Fig. 7

From: Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy

Fig. 7

Immunofluorescence assay of caspase and Ki-67 expression in the tumor areas (400×). Images of tumor tissues isolated from PBS-, EcN-, EcN (p53)-, EcN (Tum-5)-, or EcN (Tum 5-p53)-treated BALB/c nude mice bearing SMMC-7721 tumors, which were stained for caspase-3 (a) and Ki-67 (b) after intravenous injection, and the cell nucleus is stained in blue (Hoechst). Quantitative analysis of caspase-3 (c) and Ki67 (d) positive cells in the tumor areas of mice in each group (*P<0.05)

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