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Fig. 8 | Journal of Biological Engineering

Fig. 8

From: Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy

Fig. 8

In vivo toxicity assay. BALB/c nude mice were weekly treated with PBS, EcN, EcN (p53), EcN (Tum-5), and EcN (Tum 5-p53). The weights of the mice were recorded every 2 days (a). At the end of the treatment, the livers, spleens, and kidneys of five mice were excised and weighed (b). Histology of liver, spleen, kidney, lung, and heart extracted from the mice (c)

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Journal of Biological Engineering

ISSN: 1754-1611