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Fig. 2 | Journal of Biological Engineering

Fig. 2

From: Paper-based in vitro tissue chip for delivering programmed mechanical stimuli of local compression and shear flow

Fig. 2

Optimization of the type of paper, coating materials on paper, and chemical stimuli. a Average numbers of RVECs on the field-of-view (FOV) on various paper types and coatings, hole-punched into 5-mm diameter circles and cultured on a 96-well plate. b Background fluorescence intensities of two types of paper substrates. c Amount of coating materials on NC paper after washing. d-e Average numbers of migrating cells and the length of migration on the RVEC chip under static condition, with VEGF or S1P added to the central area of each chip. Averages of 3 experiments, each from 6 different images of a different paper substrate or a paper chip. Error bars represent standard errors. * represents statistical difference with p < 0.05 between two data sets (in b and c) or from control (in d and e)

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