Fig. 1
From: Signature mRNA markers in extracellular vesicles for the accurate diagnosis of colorectal cancer

EV mRNA analysis in cell lines. The relative changes in gene expression of each marker from four CRC cell lines (SW620, Wi-Dr, LS174T, and HCT116) were calculated and compared with that in a normal cell line (CCD-18Co) as the control group. EV mRNA markers were selected for further investigation if they were highly expressed in at least one CRC cell line with a relative change in gene expression of ca. 100 (ca, circa); mRNA level (a.u., arbitrary unit) running from bottom to top