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Fig. 15 | Journal of Biological Engineering

Fig. 15

From: Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

Fig. 15

A) Schematic illustration of the alginate-chitosan (Al Ch) polyionic complex hydrogel as bioink in 3D bioprinting. B) Morphological characterization of 3D bioprinted Al Ch a) 3D model of nose b) 3D printed nose, constructed by Al1Ch1.2 bioink and SEM micrograph of 3D printed Al1Ch1.0 bioink with different angles between the filaments (C1, C2) 45°, (d1, d2) 60°, (e1, e2) 90° (1,2 respectively represent front and side of the scaffold) biocompatibility of the 3D bioprinted AlCh polyionic hydrogel. C) Human adipose-derived stem cells (hASCs) were used to test the biocompatibility of the scaffold. Photographs of the inverted fluorescence microscope which represent a) live b) dead c) merged cells on the 3rd day. As shown in the pictures, the live cells distributed uniformly on the hydrogel while little or no dead cells existed. d) proliferation of hASCs distributed on the 3D bioprinted hydrogel. It showed that hASCs could proliferate during the time [127]. Liu, Q., et al., Preparation and Properties of 3D Printed Alginate–Chitosan Polyion Complex Hydrogels for Tissue Engineering. Polymers. 2018, 10(6):664.Copyright (2020)

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Journal of Biological Engineering

ISSN: 1754-1611