Fig. 3From: Heparinized chitosan stabilizes the bioactivity of BMP-2 and potentiates the osteogenic efficacy of demineralized bone matrixProtection effect of BMP-2 from noggin. a ALP staining of BMSCs cultured with graded dosages of noggin, BMP-2, and either MeGC or Hep-MeGC. Scale bar is 100 μm. b Noggin gene expression induced by BMP-2 in BMSCs. BMSCs were treated with BMP-2 up to 72 h. N.S., Not significant. *p < 0.05 compared to the negative control (white bar)Back to article page