Fig. 3From: Engineered hypoxia-responding Escherichia coli carrying cardiac peptide genes, suppresses tumor growth, angiogenesis and metastasis in vivoA In vitro cytotoxicity of purified cardiac peptides from 48 h growing media of bacteria bearing construct under hypoxic condition. B The results of Annexin-V/7-AAD flow cytometry analysis. Treating MCF-7 cells with cardiac peptides mixture significantly increased rate of apoptosis compare to PBS receiving group (Left: PBS, Middle: media of bacteria without construct, Right: cardiac peptides purified from media of bacteria bearing construct)Back to article page