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Fig. 5 | Journal of Biological Engineering

Fig. 5

From: Engineered hypoxia-responding Escherichia coli carrying cardiac peptide genes, suppresses tumor growth, angiogenesis and metastasis in vivo

Fig. 5

(A) suppression of tumor growth by administration of different concentrations of bacteria bearing construct. Increase in concentration of administered bacteria significantly enhanced tumor suppression potency. Ns: not significant, ****: P < 0.0001 compared to PBS, ####: P < 0.0001 compared to bacteria bearing construct at concentrations equal to 107 cfu/g (B) Results of Kaplan-Meyer analysis demonstrating a higher rate of survival in mice receiving bacteria bearing construct compared to PBS and bacteria without construct

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