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Fig. 2 | Journal of Biological Engineering

Fig. 2

From: Knockdown of NCK1-AS1 inhibits the development of atherosclerosis by targeting miR-1197/COX10 axis

Fig. 2

Knockdown of NCK1-AS1 attenuated ox-LDL induced cell injury in VSMCs. VSMCs were transfected with sh-NCK1-AS1 or sh-NC, and then treated with 50 μg/ml ox-LDL for 24 h. A The expression of NCK1-AS1 was detected by qRT-PCR. B CCK-8 assay. C MDA content was measured by specific detection kit. D Flow cytometry for cell apoptosis. E The expression of cleaved caspase3, Bax and Bcl-2 was measured by western blot. Control group is that VSMCs without any treatment, NC means that VSMCs received ox-LDL treatment. * p < 0.05, ** p < 0.01 and *** p < 0.001

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