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Fig. 1 | Journal of Biological Engineering

Fig. 1

From: Robust network topologies for temperature-inducible bioswitches

Fig. 1

A Image for comparison between a traditional switch based on temperature-sensitive biomolecules and our scheme based on appropriately designed network topologies of biomolecular interactions governed by the Arrhenius law. B-C Flowsheet for screening functional TIS networks. The enumerated topologies, the adjacent matrix, and the corresponding rate equations (B). Schematic diagram for random sampling of the parameter space (top left) and target functional concentration-temperature dependencies for the Off–On, On–Off, and Off–On-Off TIS switches (C)

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