Fig. 3

a Scheme and SEM image of Dtxl-encapsulated NPs. b The comparative efficacy study of single intratumoral injection (day 0) of saline, PEGylated PLGA NP without drug (NP), emulsified Dtxl (Dtxl), Dtxl-encapsulated NPs (Dtxl-NP), or Dtxl-encapsulated NP-Apt bioconjugates (Dtxl-NP-Apt). A representative mouse at the end point (>109 days) for each group is shown (Left) alongside images of excised tumors (Right). Black arrows indicate the position of the implanted tumor on each mouse. Reproduced with permission from ref. 40; Copyright 2006 PNAS