Skip to main content
Fig. 6 | Journal of Biological Engineering

Fig. 6

From: Exosomes derived from microRNA-138-5p-overexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2

Fig. 6

Endocytosis, intracellular sorting, and processing of BMSCs-derived exosomes by astrocytes. a, electron microscopic examination of exosomes (scale bar = 200 nm); b, protein bands of surface makers of BMSCs-derived exosomes determined by Western blot analysis (CL, BMSC lysate; EXO, exosomes); c, quantitative analysis regarding protein expression of surface makers of BMSCs-derived exosomes determined by Western blot analysis; d, exosome surface fluorescence (scale bar = 25 μm); e, quantitative analysis for endocytosis at different time points. The data were all expressed as mean ± standard deviation. The comparison between two groups was analyzed by non-paired t-test. The experiment was repeated three times. *, p < 0.05 vs. CL or endocytosis at 12 h. BMSCs, bone marrow-derived mesenchymal stem cells

Back to article page

Journal of Biological Engineering

ISSN: 1754-1611