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Fig. 6 | Journal of Biological Engineering

Fig. 6

From: Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation

Fig. 6

Effects of exosomes derived from HK2 cells under different conditions on oxidative stress injury and the MAPK signalling pathway in rat renal tissues with different treatments. A Measurement of CAT activity in the SD rats with different treatments. B MDA expression in the SD rats under different conditions. C SOD activity of the SD rats with different treatments. D ROS levels in the SD rats under different conditions. The expression of P-P38 was increased in the rats injected with EXO(S) or injected with GAM, pre-EXO(C) renal subcapsular injection could ameliorate these effects while pre-EXO(S) renal subcapsular injection could accelerate the expression of P-P38. There were no significant changes in the expression of P-JNK and P-ERK. The data are expressed as the mean ± SE. ∗P < 0.05

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Journal of Biological Engineering

ISSN: 1754-1611