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Journal of Biological Engineering

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  1. Content type: Review

    The blood-brain barrier (BBB) is the interface between the vasculature and the brain, regulating molecular and cellular transport into the brain. Endothelial cells (ECs) that form the capillary walls constitut...

    Authors: John J. Jamieson, Peter C. Searson and Sharon Gerecht

    Citation: Journal of Biological Engineering 2017 11:37

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  2. Content type: Methodology

    In the past two decades, methods have been developed to measure the mechanical properties of single biomolecules. One of these methods, Magnetic tweezers, is amenable to aquisition of data on many single molec...

    Authors: Keith C. Johnson, Emilie Clemmens, Hani Mahmoud, Robin Kirkpatrick, Juan C. Vizcarra and Wendy E. Thomas

    Citation: Journal of Biological Engineering 2017 11:47

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  3. Content type: Review

    Liver disease contributes significantly to global disease burden and is associated with rising incidence and escalating costs. It is likely that innovative approaches, arising from the emerging field of liver ...

    Authors: Ogechi Ogoke, Janet Oluwole and Natesh Parashurama

    Citation: Journal of Biological Engineering 2017 11:46

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  4. Content type: Research

    Electronic lab notebooks (ELNs) are better equipped than paper lab notebooks (PLNs) to handle present-day life science and engineering experiments that generate large data sets and require high levels of data ...

    Authors: Erin M. Riley, Holly Z. Hattaway and P. Arthur Felse

    Citation: Journal of Biological Engineering 2017 11:40

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  5. Content type: Methodology

    Targeted nucleases have transformed genome editing technology, providing more efficient methods to make targeted changes in mammalian genome. In parallel, there is an increasing demand of Cre-LoxP technology f...

    Authors: Ranjita Sengupta, Amy Mendenhall, Nandita Sarkar, Chandreyee Mukherjee, Amirali Afshari, Joseph Huang and Biao Lu

    Citation: Journal of Biological Engineering 2017 11:45

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  6. Content type: Research

    This study examines the effects of adding gelatin to a starch-chitosan composite foam, focusing on the altered structural and biological properties. The compressive modulus of foams containing different gelati...

    Authors: Gregory E. Risser, Brittany L. Banik, Justin L. Brown and Jeffrey M. Catchmark

    Citation: Journal of Biological Engineering 2017 11:43

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  7. Content type: Research

    Previously we demonstrated that an entire bacterial operon (the PRN operon) is expressible in plants when driven by the Tomato -yellow-leaf-curl-virus (TYLCV) -derived universal vector IL-60.

    Authors: Rita Mozes-Koch, Edna Tanne, Alexandra Brodezki, Ran Yehuda, Ofer Gover, Haim D. Rabinowitch and Ilan Sela

    Citation: Journal of Biological Engineering 2017 11:44

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  8. Content type: Review

    The accumulated evidence points to the microenvironment as the primary mediator of cellular fate determination. Comprised of parenchymal cells, stromal cells, structural extracellular matrix proteins, and sign...

    Authors: Patrick C. Sachs, Peter A. Mollica and Robert D. Bruno

    Citation: Journal of Biological Engineering 2017 11:34

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  9. Content type: Methodology

    Locomotor activity of rodents is an important readout to assess well-being and physical health, and is pivotal for behavioral phenotyping. Measuring homecage-activity with standard and cost-effective optical m...

    Authors: Andreas Genewsky, Daniel E. Heinz, Paul M. Kaplick, Kasyoka Kilonzo and Carsten T. Wotjak

    Citation: Journal of Biological Engineering 2017 11:36

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  10. Content type: Letters to the Editor

    Oxygen-responsive promoters can be useful for synthetic biology applications, however, information on their characteristics is still limited. Here, we characterized a group of heterologous microaerobic globin ...

    Authors: Alvaro R. Lara, Karim E. Jaén, Juan-Carlos Sigala, Lars Regestein and Jochen Büchs

    Citation: Journal of Biological Engineering 2017 11:39

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  11. Content type: Research

    Aerobic granular sludge has become an attractive alternative to the conventional activated sludge due to its high settling velocity, compact structure, and higher tolerance to toxic substances and adverse cond...

    Authors: Yanan Ren, Fernanda Ferraz, Abbass Jafari Kang and Qiuyan Yuan

    Citation: Journal of Biological Engineering 2017 11:42

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  12. Content type: Research

    This article explains some simple experiments that can be used in undergraduate or graduate physics or biomedical engineering laboratory classes to learn how birdcage volume radiofrequency (RF) coils and magne...

    Authors: Dwight E. Vincent, Tianhao Wang, Thalia A. K. Magyar, Peni I. Jacob, Richard Buist and Melanie Martin

    Citation: Journal of Biological Engineering 2017 11:41

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  13. Content type: Research

    UP elements (upstream element) are DNA sequences upstream of a promoter that interact with the α-subunit of RNA polymerase (RNAP) and can affect transcription by altering the binding RNAP to DNA. However, deta...

    Authors: Qiang Yan and Stephen S. Fong

    Citation: Journal of Biological Engineering 2017 11:33

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  14. Content type: Research

    Human induced pluripotent stem cells (hiPSCs) can form any tissue found in the body, making them attractive for regenerative medicine applications. Seeding hiPSC aggregates into biomaterial scaffolds can contr...

    Authors: Meghan E. Hall, Nima Khadem Mohtaram, Stephanie M. Willerth and Roderick Edwards

    Citation: Journal of Biological Engineering 2017 11:38

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  15. Content type: Research

    The primary objective of Tissue engineering is a regeneration or replacement of tissues or organs damaged by disease, injury, or congenital anomalies. At present, Tissue engineering repairs damaged tissues and...

    Authors: Aleš Gregor, Eva Filová, Martin Novák, Jakub Kronek, Hynek Chlup, Matěj Buzgo, Veronika Blahnová, Věra Lukášová, Martin Bartoš, Alois Nečas and Jan Hošek

    Citation: Journal of Biological Engineering 2017 11:31

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  16. Content type: Research

    The antibiotic methylenomycin A is produced naturally by Streptomyces coelicolor A3(2), a model organism for streptomycetes. This compound is of particular interest to synthetic biologists because all of the a...

    Authors: Jack E. Bowyer, Emmanuel LC. de los Santos, Kathryn M. Styles, Alex Fullwood, Christophe Corre and Declan G. Bates

    Citation: Journal of Biological Engineering 2017 11:30

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  17. Content type: Research

    With additive manufacturing (AM) individual and biocompatible implants can be generated by using suitable materials. The aim of this study was to investigate the biological effects of polylactic acid (PLA) man...

    Authors: Matthias C. Wurm, Tobias Möst, Bastian Bergauer, Dominik Rietzel, Friedrich Wilhelm Neukam, Sandra C. Cifuentes and Cornelius von Wilmowsky

    Citation: Journal of Biological Engineering 2017 11:29

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  18. Content type: Review

    Due to steadily growing population and economic transitions in the more populous countries, renewable sources of energy are needed more than ever. Plant biomass as a raw source of bioenergy and biofuel product...

    Authors: Ahmed Debez, Ikram Belghith, Jan Friesen, Carsten Montzka and Skander Elleuche

    Citation: Journal of Biological Engineering 2017 11:27

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  19. Content type: Research

    In the yeast Saccharomyces cerevisiae, as in every eukaryotic organism, the mRNA 5-untranslated region (UTR) is important for translation initiation. However, the patterns and mechanisms that determine the effic...

    Authors: Jing Li, Qiang Liang, Wenjiang Song and Mario Andrea Marchisio

    Citation: Journal of Biological Engineering 2017 11:25

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  20. Content type: Research

    The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a...

    Authors: Markus J. Schmidt, David Sauter and Thomas Rösgen

    Citation: Journal of Biological Engineering 2017 11:24

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  21. Content type: Research

    The configuration of necrotic areas within the retinal pigmented epithelium is an important element in the progression of age-related macular degeneration (AMD). In the exudative (wet) and non-exudative (dry) ...

    Authors: Qanita Bani Baker, Gregory J. Podgorski, Elizabeth Vargis and Nicholas S. Flann

    Citation: Journal of Biological Engineering 2017 11:26

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  22. Content type: Research

    Poly(γ-glutamic acid) (γ-PGA) is a biopolymer with many useful properties making it applicable for instance in food and skin care industries, in wastewater treatment, in biodegradable plastics or in the pharma...

    Authors: Lena Regestein née Meissner, Julia Arndt, Thomas G. Palmen, Tim Jestel, Hitoshi Mitsunaga, Eiichiro Fukusaki and Jochen Büchs

    Citation: Journal of Biological Engineering 2017 11:23

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