Figure 1

Effect of BSA on Aβ _1–40 monomer aggregation. Aβ_1–40 monomer was diluted to 20 μM in buffer containing 150 mM NaCl and 40 mM Tris-HCl (pH 8.0) and incubated alone (control, [white circle]) or in the presence of 20 μM [black square], 40 μM [black triangle], or 80 μM [black diamond] BSA. Aggregation of monomer was induced by continuous agitation and monitored using thioflavin T fluorescence. Results are representative of three independent experiments.