Table 3 Results of utilizing Hertz contact theory to calculate elastic modulus of axons with and without cytoskeleton disruption
From: Contribution of cytoskeletal elements to the axonal mechanical properties
Drug | Disrupt cytoskeleton | Elastic modulus of axon, E2(Pa) |
|---|---|---|
Control (no drug) | None | 9,500 |
Nocodazole | Microtubule | 1,470 |
Cytochalasin D | Microfilament | 5,785 |
Acrylamide | Neurofilament | 3,425 |
All 3 drugs | All 3 elements | 2,010 |