Figure 7
Comparison between measured and calculated k L a values at 25°C for Corning roller bottles (2 L), Nalgene vessels (10 L, 20 L, 50 L) and CultiBag ORB (200 L) bioreactors. Shaking frequencies of between 60 rpm and 220 rpm and relative filling volumes between 25% and 75%. Open symbols indicate values for n < NC or d0/d <0.06. Values measured with water and sulfite solutions with 0.5 M and 1 M Na2SO3, 10-7 M CoSO4, 0.012 M phosphate buffer and initial pH = 8.