Table 2 Synergistic effect between SDF-1α and other bioactive factors
From: Delivery of stromal cell-derived factor 1α for in situ tissue regeneration
Bonding strategy | Factors | Implant position | Scaffold | References |
|---|---|---|---|---|
Direct loading or adsorption (Adsorb solution through inject) | SDF-1α and BMP-2 | Mouse, calvarial defects | Commercial collagena | [94] |
Gelatin hydrogels | [95] | |||
Direct loading or adsorption (Direct loading during manufacture process) | Mouse, ulna critical-sized defect | Degradable hydrogels | [96] | |
Mouse, calvarial defects/ subcutaneous sites | Commercial collagenb | [97] | ||
SDF-1α and VEGF | Mouse, calvarial defects/ subcutaneous sites | Commercial collagenb | [97] | |
SDF-1α and platelet-derived growth factor (PDGF) | Mouse, calvarial defects/ subcutaneous sites | Commercial collagenb | [97] | |
SDF-1α and simvastatin | Mouse, calvarial defects | PLGA | [117] | |
SDF-1α and insulin-like growth factor-1 (IGF-1) | Rat, lateral gastrocnemius muscle of the TK-injured limb | PEGylated fibrin gel matrix | [98] |